I'm looking for a way to create keepouts for specific nets. Actually a keepout for every net except "GND" (return). Our current process involves importing mechanical housings/isolation covers into Allegro (dxf) and manually reviewing for minimum clearances. This is not a very good process. The attached image shows the isolation walls(red) and soldermask (violet). The image is a small fraction of the area that we need to verify.
Needless to say, on occasion we've missed a spot or two.